Endometrial dating infertility
The pars functionalis is known as the decidua during pregnancy, when it underlies the placenta. The mucous membrane forming the inner layer of the uterine wall; it consists of a simple columnar epithelium and a lamina propria that contains simple tubular uterine glands.
the lining of the uterus in female mammals, being a glandular MUCUS membrane that undergoes changes during the OESTRUS CYCLE during which it builds up under the influence of OESTROGEN in preparation for receiving the fertilized egg.
The blastocyst implants into the endometrium making the uterus gravid.
If implantation does not occur, the superficial part of the endometrium is shed during the (hemorrhagic) menstrual phase of the uterine mucous membrane lining of the uterus, consisting of the stratum compactum, the stratum spongiosum, and the stratum basale.
Results did not substantially differ using alternative definitions of "out-of-phase" or standardized cycle day.
CONCLUSION(S): Histological dating of the endometrium does not discriminate between women of fertile and infertile couples and should not be used in the routine evaluation of infertility.
Criterion standard for infertility was 12 months of unprotected, regular intercourse without conception and for fertility at least one live birth within 2 years. PATIENT(S): Volunteer subjects (847) recruited at 12 clinical sites participating in the National Institutes of Health-funded Reproductive Medicine Network.
An endometrial biopsy that shows a difference of more than 2 days between the histologic dating and actual day after ovulation is considered to be "out of phase" However, the clinical application of the Noyes criterion is relatively limited.
Two hundred and thirty-two women with primary or secondary infertility were divided into four groups according to their endometrial biopsy result: 114 (49%) with no delay of the secretory phase, 36 (16%) with a secretory phase with a delay of 2 days, 26 (11%) with a secretory delay of 3 days or more, and 56 (24%) with an endometrium which could not be dated because of inadequate material.
Where fertilization does not occur, it regresses, or in the case of humans, anthropoid apes and Old-World monkeys, it breaks down over a few days, producing bleeding. Expression and regulation of prostaglandin transporters, ATP-binding cassette, subfamily C, member 1 and 9, and solute carrier organic anion transporter family, member 2A1 and 5A1 in the uterine endometrium during the estrous cycle and pregnancy in pigs cancer, and it is widely considered to develop from endometrial intraepithelial carcinoma, which is related to malignant transformation of the endometrial surface epithelium (such as a benign endometrial polyp).
is the best accessible tissue for histopathological evaluation of uterine bleeding, several methods are used for endometrial sampling among which the dilatation of the cervix and curettage of the uterine cavity under general anaesthesia has long been the gold standard for the assessment of AUB.